Art Kleiner is the editor-in-chief of strategy+business, a management magazine published since 1996, and editor-in-chief for PwC's global thought leadership. He is the coauthor, with Jeffrey Schwartz and Josie Thomson, of The Wise Advocate: The Inner Voice of Strategic Leadership (Columbia University Business Press, 2019). Kleiner has been an adjunct faculty member at New York University’s Interactive Telecommunications Program since 1987, and was the editorial director of Peter Senge's Fifth Discipline Fieldbook project. Since 2021, he has served as a Principal Consultant at Kleiner Powell International.

In the late 1970s, Kleiner was one of the first journalists to write about the communications systems that would become the internet, in articles for CoEvolution Quarterly and the Whole Earth Catalog, where he was an editor in the 1980s. His book The Age of Heretics: A History of the Radical Thinkers Who Reinvented Corporate Management (1996 and 2008), was praised by Howard Rheingold as "a landmark for people inside and outside the most influential institution of the modern age -- the corporation." Marc Andreesen said his book Who Really Matters: The Core Group Theory of Power, Privilege and Success is “perhaps the best underappreciated business book ever written." Kleiner was also the editorial director of the Fifth Discipline Fieldbook series, a longstanding writer on management, and a consultant on scenario planning and leadership development. He has given keynote addresses at a variety of locales (most recently at the 2018 annual Drucker Forum), taught regularly at the Shambhala Institute for Authentic Leadership and co-created (with George Roth) a pioneering form of organizational storytelling called the "learning history" at MIT's Center for Organizational Learning.